Claim Profile. We are currently investigating potential therapeutic options to ameliorate the robust inflammatory response neonates mount when challenged with an infection.I have been extremely lucky to have strong mentorship from both the Department of Pediatrics (Maria Delivoria-Papadopoulos, MD) and Department of Microbiology and Immunology (Peter Katsikis MD, PhD). I have developed a preterm animal model of influenza infection in order to further delineate what makes infants exquisitely sensitive to infections. Specifically, influenza infection leads to many hospitalizations and deaths each year, mainly in children and the elderly. Drexel University College of Medicine clinician teachers, faculty and residents provide a critical component of medical student education. However, up to this point, there have not been investigations into the use of intranasal probiotics for respiratory infections in infants. Death and disability from influenza (flu) infection is highest in infants younger than 6 months, an age group not currently eligible for flu vaccines. ... Alison Carey, MD, Drexel University College of Medicine *Navigating the IRB.
Read Dr. Carey's faculty highlight from the Women in Medicine and Science Committee. I have also served as a mentor to several of the neonatology fellows at St. Christopher's Hospital. The mortality rate from influenza infection is highest in infants less thn the age of six months, which is currently an age group not eligible for the available influenza vaccine.
Kristie Cox. / Drexel University: $171,904 Publications. There are little data on why neonates exhibit increased mortality to influenza virus, although we know they do not have the mature, full immune repertoire that adults have at their disposal. Alison J. Carey, MD, is an associate professor of pediatrics at Drexel University College of Medicine.Dr. By using our novel neonatal mouse model, we are proposing studies to determine the critical differences in how the neonatal mice respond to influenza virus infection. 2) Determine whether providing a probiotic will help protect neonatal mice from influenza infection. Eligibility Neonatal Perinatal Medicine. Drexel University College of Medicine Could Probiotics Help Prevent and Treat Infant Influenza? This Career Development Award will serve as a driving force in Dr. Carey's success, providing the protected time and additional training required for this candidate to become an independent investigator.Influenza virus infection is particularly dangerous during the first few months of life. Dr. Carey is a Neonatologist and has a dual appointment as an Assistant Professor of Pediatrics and Microbiology/Immunology at Drexel University College of Medicine.
Alison J. Carey, MD, Associate Professor Pediatrics, Drexel University for Targeted Blockade of Toll-like Receptors in Respiratory Viral Infection Eileen T. Chambers, MD, Associate Professor Pediatrics, Duke University for an Acoustic Device to … Alison has 4 jobs listed on their profile.
Using an acute influenza infection model, we have examined the TCR repertoire of the CTL response in neonatal and adult mice infected with influenza type A virus.
In our preliminary work, we determined that when 3-day old mice are infected with influenza, there is a high rate of death, approaching 80% by 8 days post infection. We are currently investigating the development of the T cell repertoire during repeat viral challenges using our In our preliminary work, we have determined that neonate mortality approaches 80 percent by eight days post-infection with influenza, with viral loads higher during early infection in neonates compared to adult mice. "Lung transcriptional unresponsiveness and loss of early influenza virus control in infected neonates is prevented by intranasal Lactobacillus rhamnosus GG" Kumova OK, Fike AJ, Thayer JL, Nguyen LT, Mell JC, Pascasio J, Stairiker C, Leon LG, Katsikis PD, Carey AJ PLoS Pathog.
Georgetown University … Institution: Drexel University College of Medicine.
I have been mentoring a young woman for the past two years, who is now a member of Drexel College of Medicine's Class of 2018. Neonatology is a comparatively new field in medicine and there are many knowledge gaps, which makes it fertile ground for research.A career in medicine and science is a marathon, not a sprint, and so pacing yourself is of critical importance. Carey's research seeks to identify mechanisms and potential modifiable risk factors for infants' susceptibility to infections using animal models, Dr. Carey was awarded a biomedical research grant from the American Lung Association for her project, "Identification of the Toll-like Receptor Mediating Drexel University, College of Medicine, 2900 W. Queen Lane, Philadelphia, PA 19129,
This knowledge may allow us to develop novel therapeutic strategies against viral respiratory infections that reduce morbidity and mortality in neonates. Alison Carey, MD, Section Chief Fellowship Training: Morgan Stanley Children's Hospital of New York Presbyterian Medical Center, Columbia University.
As a neonatologist, Alison Carey, M.D., sees many premature babies in the neonatal intensive care unit (NICU) who develop lung infections.
Alison Carey, MD, is an attending neonatologist at St. Christopher's Hospital for Children. "Infections are a major cause of death for these babies," says Dr. Carey, Assistant Professor of Pediatrics and Immunology at Drexel University College of Medicine in Philadelphia.
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